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PhD defense: Mikkel Karl Emil Nygaard

CFIN researcher in the Applied Imaging and Modelling group (AIM), Mikkel Karl Emil Nygaard will defend his PhD thesis entitled: "Clinical feasible MRI markers of disability and disease pathology in relapsing-remitting multiple sclerosis".

Info about event


Friday 16 June 2023,  at 12:30 - 14:30


Thalamus meeting room, CFIN South, Building 1710, Universitetsbyen 3, 8000 Aarhus C.


CFIN / Associate professor Simon Fristed Eskildsen
PhD student Mikkel Karl Emil Nygaard

Mikkel Karl Emil Nygaard
"Clinical feasible MRI markers of disability and disease pathology in relapsing-remitting multiple sclerosis"

Main supervisor: Associate professor, Simon Fristed Eskildsen, CFIN, Aarhus University

About the PhD thesis:

New PhD-study investigates clinical feasible MRI markers of disability and disease pathology in multiple sclerosis.

Magnetic resonance imaging (MRI) paraclinically supports the diagnosis of relapse-remitting multiple sclerosis (RRMS) and monitoring of disease progression. This relies on the occurence of brain lesions or dissemination of existing lesions together with progression of disease related disability. New MRI methods can quantify the microstructure of the brain and thus potentially can detect changes at cellular level, which precede the conventional measures of macroscopic lesions. Additionally, the method can detect degeneration in areas outside lesions and among these, areas related to the disease induced symptoms of MS.

The relationship between the microstructure and disease disability and pathology in patients with RRMS is studied in a new PhD project at Aarhus University. The study was carried out by Mikkel Karl Emil Nygaard, who has applied novel imaging and data analysis methods to measure and visualize the pathologi in the brain. The results of the project contribute to the understanding of degeneration in the brain of patients with RRMS and how it reflects disease disability.

Assessment committee:

  • Christoffer Laustsen, Professor, The MR Research Centre, Aarhus University, Aarhus, Denmark
  • Jan-Patrick Stellmann, Associate professor, Center for Magnetic Resonance in Biology and Medicine, Aix Marseille Université, Marseille, France
  • Henrik Lundell, Senior Researcher, Danish Research Centre for Magnetic Resonance, Copenhagen University Hospitals, Denmark

After the defense CFIN will host a small reception in the pavilion, Building 1710.

Zoom link for online participation:

For more information, please contact:
PhD student Mikkel Karl Emil Nygaard
Email: mken@cfin.au.dk
Phone +45 4083 4740.